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mRNA 3′ uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome

A fundamental principle in biology is that the program for early development is established during oogenesis in the form of the maternal transcriptome1,2. How the maternal transcriptome acquires the appropriate content and dosage of transcripts is not fully understood. Here we show that TUT4/7-media...

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Detalles Bibliográficos
Autores principales: Morgan, Marcos, Much, Christian, DiGiacomo, Monica, Azzi, Chiara, Ivanova, Ivayla, Vitsios, Dimitrios M., Pistolic, Jelena, Collier, Paul, Moreira, Pedro, Benes, Vladimir, Enright, Anton J., O’Carroll, Dónal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768236/
https://www.ncbi.nlm.nih.gov/pubmed/28792939
http://dx.doi.org/10.1038/nature23318