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Pluripotent state transitions coordinate morphogenesis in mouse and human embryos

The foundations of mammalian development lie in a cluster of embryonic epiblast stem cells that, in response to extracellular matrix signalling, undergo epithelialization creating an apical surface in contact with a cavity1,2, a fundamental event for all subsequent development. Concomitantly, epibla...

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Detalles Bibliográficos
Autores principales: Shahbazi, Marta N., Scialdone, Antonio, Skorupska, Natalia, Weberling, Antonia, Recher, Gaelle, Zhu, Meng, Jedrusik, Agnieszka, Devito, Liani G., Noli, Laila, Macaulay, Iain C., Buecker, Christa, Khalaf, Yakoub, Ilic, Dusko, Voet, Thierry, Marioni, John C., Zernicka-Goetz, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768241/
https://www.ncbi.nlm.nih.gov/pubmed/29186120
http://dx.doi.org/10.1038/nature24675