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Pluripotent state transitions coordinate morphogenesis in mouse and human embryos
The foundations of mammalian development lie in a cluster of embryonic epiblast stem cells that, in response to extracellular matrix signalling, undergo epithelialization creating an apical surface in contact with a cavity1,2, a fundamental event for all subsequent development. Concomitantly, epibla...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768241/ https://www.ncbi.nlm.nih.gov/pubmed/29186120 http://dx.doi.org/10.1038/nature24675 |