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Long-term administration of tacrolimus and everolimus prevents high cholesterol-high fructose-induced steatosis in C57BL/6J mice by inhibiting de-novo lipogenesis

AIM: To investigate the effects of tacrolimus (TC) and everolimus (EV) on non-alcoholic steatohepatitis (NASH) induced by high fat, high cholesterol and fructose (fast food) diet in C57BL/6J mice. MATERIALS AND METHODS: C57BL/6J mice were divided into four groups (n=8). 1) Standard Chow (SC); 2) Fas...

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Detalles Bibliográficos
Autores principales: Love, Sharma, Mudasir, Malik A., Bhardwaj, Subhash C., Singh, Gurdarshan, Tasduq, Sheikh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768335/
https://www.ncbi.nlm.nih.gov/pubmed/29371918
http://dx.doi.org/10.18632/oncotarget.15194