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Hypermethylation of BEND5 contributes to cell proliferation and is a prognostic marker of colorectal cancer

Aberrant hypermethylation of CpG islands in tumor suppressor genes (TSGs) contributes to colorectal tumorigenesis. To identify new colorectal cancer (CRC) screening marker, we investigated DNA methylation alterations in novel TSGs. Using HumanMethylation450 BeadChip arrays, CpG regions in BEND5 were...

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Detalles Bibliográficos
Autores principales: Lin, Ruo-Kai, Hung, Wan-Yu, Huang, Yu-Fang, Chang, Yu-Jia, Lin, Chien-Hsing, Chen, Wei-Yu, Chiu, Shih-Feng, Chang, Shih-Ching, Tsai, Shih-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768337/
https://www.ncbi.nlm.nih.gov/pubmed/29371920
http://dx.doi.org/10.18632/oncotarget.22266