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Hypermethylation of BEND5 contributes to cell proliferation and is a prognostic marker of colorectal cancer
Aberrant hypermethylation of CpG islands in tumor suppressor genes (TSGs) contributes to colorectal tumorigenesis. To identify new colorectal cancer (CRC) screening marker, we investigated DNA methylation alterations in novel TSGs. Using HumanMethylation450 BeadChip arrays, CpG regions in BEND5 were...
Autores principales: | Lin, Ruo-Kai, Hung, Wan-Yu, Huang, Yu-Fang, Chang, Yu-Jia, Lin, Chien-Hsing, Chen, Wei-Yu, Chiu, Shih-Feng, Chang, Shih-Ching, Tsai, Shih-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768337/ https://www.ncbi.nlm.nih.gov/pubmed/29371920 http://dx.doi.org/10.18632/oncotarget.22266 |
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