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Independent replication of polymorphisms predicting toxicity in breast cancer patients randomized between dose-dense and docetaxel-containing adjuvant chemotherapy

INTRODUCTION: Although pharmacogenomics has evolved substantially, a predictive test for chemotherapy toxicity is still lacking. We compared the toxicity of adjuvant dose-dense doxorubicin-cyclophosphamide (ddAC) and docetaxel-doxorubicin-cyclophosphamide (TAC) in a randomized multicenter phase III...

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Detalles Bibliográficos
Autores principales: van Rossum, Annelot G.J., Kok, Marleen, McCool, Danielle, Opdam, Mark, Miltenburg, Nienke C., Mandjes, Ingrid A.M., van Leeuwen-Stok, Elise, Imholz, Alex L.T., Portielje, Johanneke E.A., Bos, Monique M.E.M., van Bochove, Aart, van Werkhoven, Erik, Schmidt, Marjanka K., Oosterkamp, Hendrika M., Linn, Sabine C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768344/
https://www.ncbi.nlm.nih.gov/pubmed/29371927
http://dx.doi.org/10.18632/oncotarget.22697