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Ubiquitin carboxyl-terminal hydrolase isozyme L5 inhibits human glioma cell migration and invasion via downregulating SNRPF

Ubiquitin C-terminal Hydrolase-L5 (UCH-L5/UCH37), a member of the deubiquitinases (DUBs), suppresses protein degeneration via removing ubiquitin from the distal subunit of the polyubiquitin chain. The activity of UCH-L5 is enhanced when UCH-L5 combines with proteasome 19S regulatory subunit by Rpn13...

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Detalles Bibliográficos
Autores principales: Ge, Jiafeng, Hu, Weiwei, Zhou, Hui, Yu, Juan, Sun, Chongran, Chen, Weilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768352/
https://www.ncbi.nlm.nih.gov/pubmed/29371935
http://dx.doi.org/10.18632/oncotarget.23071