Elucidating respective functions of two domains BIR and C-helix of human IAP survivin for precise targeted regulating mitotic cycle, apoptosis and autophagy of cancer cells

Survivin was the smallest member of the IAP family, which was over expressed in many different cancers, and considered to be a promising hot target for cancer therapy, and our previous study demonstrated that multiple dominant negative mutants from full-length survivin could have many complex effect...

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Detalles Bibliográficos
Autores principales: Hu, Fabiao, Pan, Daxia, Zheng, Wenyun, Yan, Ting, He, Xiujuan, Ren, Fuzheng, Lu, Yiming, Ma, Xingyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768356/
https://www.ncbi.nlm.nih.gov/pubmed/29371939
http://dx.doi.org/10.18632/oncotarget.22823

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768356/
https://www.ncbi.nlm.nih.gov/pubmed/29371939
http://dx.doi.org/10.18632/oncotarget.22823

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