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Overexpression of miR-489 enhances efficacy of 5-fluorouracil-based treatment in breast cancer stem cells by targeting XIAP

Population of cancer stem cells (CSCs) in breast cancer is reported to be resistant to chemotherapy. Furthermore, many cases of treatment failure are induced by the chemoresistance of CSCs in breast cancer patients. Therefore, novel strategies should be explored urgently to reverse drug-resistance i...

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Detalles Bibliográficos
Autores principales: Wang, Xuedong, Wang, Xinguo, Gu, Juan, Zhou, Ming, He, Zhimin, Wang, Xinhui, Ferrone, Soldano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768367/
https://www.ncbi.nlm.nih.gov/pubmed/29371950
http://dx.doi.org/10.18632/oncotarget.22985