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Novel proteasome inhibitor delanzomib sensitizes cervical cancer cells to doxorubicin-induced apoptosis via stabilizing tumor suppressor proteins in the p53 pathway

Cervical cancer, the third most commonly occurring cancer, is the second leading cause of cancer related mortality among women. Aberrant ubiquitination and proteasome activity, both human papillomavirus and tumor derived, have been shown to contribute to tumor angiogenesis, proliferation, and invasi...

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Detalles Bibliográficos
Autores principales: Guo, Kevin Y., Han, Lili, Li, Xinyu, Yang, Andrew V., Lu, Jiaxiong, Guan, Shan, Li, Hui, Yu, Yang, Zhao, Yanling, Yang, Jianhua, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768391/
https://www.ncbi.nlm.nih.gov/pubmed/29371974
http://dx.doi.org/10.18632/oncotarget.23166