CDC5L drives FAH expression to promote metabolic reprogramming in melanoma

Metabolic reprogramming allows tumor cells to thrive in the typically hypoxic tumor microenvironment. Using immunodetection and clinical data analyses, we demonstrate here that fumarylacetoacetate hydrolase (FAH) is highly expressed in melanoma and correlates with poor survival. FAH knockdown inhibi...

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Detalles Bibliográficos
Autores principales: Gu, Zhichao, Zhang, Huafeng, Li, Yong, Shen, Susu, Yin, Xiaonan, Zhang, Wei, Cheng, Ruimin, Zhang, Yong, Zhang, Xiaoyan, Chen, Hui, Huang, Bo, Cao, Yuchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768407/
https://www.ncbi.nlm.nih.gov/pubmed/29371990
http://dx.doi.org/10.18632/oncotarget.23107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768407/
https://www.ncbi.nlm.nih.gov/pubmed/29371990
http://dx.doi.org/10.18632/oncotarget.23107

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