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Genomic alterations of ERBB receptors in cancer: clinical implications

The ERBB family of receptor tyrosine kinases has been implicated in carcinogenesis for over three decades with rigorous attention to EGFR and HER2. ERBB receptors, consisting of EGFR, HER2, HER3, and HER4 are part of a complicated signaling network that activates downstream signaling pathways includ...

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Detalles Bibliográficos
Autores principales: Mishra, Rosalin, Hanker, Ariella B., Garrett, Joan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768410/
https://www.ncbi.nlm.nih.gov/pubmed/29371993
http://dx.doi.org/10.18632/oncotarget.22825