Cargando…
PERK-mediated translational control is required for collagen secretion in chondrocytes
As chondrocytes are highly secretory and they experience a variety of stresses, physiological unfolded protein response (UPR) signalling is essential for extracellular matrix (ECM) secretion and chondrogenesis. In the three branches of the UPR pathway, PERK governs the translational attenuation and...
Autores principales: | Hisanaga, Satoshi, Miyake, Masato, Taniuchi, Shusuke, Oyadomari, Miho, Morimoto, Masatoshi, Sato, Ryosuke, Hirose, Jun, Mizuta, Hiroshi, Oyadomari, Seiichi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768675/ https://www.ncbi.nlm.nih.gov/pubmed/29335505 http://dx.doi.org/10.1038/s41598-017-19052-9 |
Ejemplares similares
-
Ligand-induced rapid skeletal muscle atrophy in HSA-Fv2E-PERK transgenic mice
por: Miyake, Masato, et al.
Publicado: (2017) -
Integrated stress response of vertebrates is regulated by four eIF2α kinases
por: Taniuchi, Shusuke, et al.
Publicado: (2016) -
Integrated stress response regulates GDF15 secretion from adipocytes, preferentially suppresses appetite for a high-fat diet and improves obesity
por: Miyake, Masato, et al.
Publicado: (2021) -
Nanosecond pulsed electric fields induce the integrated stress response via reactive oxygen species-mediated heme-regulated inhibitor (HRI) activation
por: Hamada, Yoshimasa, et al.
Publicado: (2020) -
Cell-based HTS identifies a chemical chaperone for preventing ER protein aggregation and proteotoxicity
por: Kitakaze, Keisuke, et al.
Publicado: (2019)