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Tumor-derived exosomal miR-1247-3p induces cancer-associated fibroblast activation to foster lung metastasis of liver cancer

The communication between tumor-derived elements and stroma in the metastatic niche has a critical role in facilitating cancer metastasis. Yet, the mechanisms tumor cells use to control metastatic niche formation are not fully understood. Here we report that in the lung metastatic niche, high-metast...

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Detalles Bibliográficos
Autores principales: Fang, Tian, Lv, Hongwei, Lv, Guishuai, Li, Ting, Wang, Changzheng, Han, Qin, Yu, Lexing, Su, Bo, Guo, Linna, Huang, Shanna, Cao, Dan, Tang, Liang, Tang, Shanhua, Wu, Mengchao, Yang, Wen, Wang, Hongyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768693/
https://www.ncbi.nlm.nih.gov/pubmed/29335551
http://dx.doi.org/10.1038/s41467-017-02583-0