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Increased Expression of GLP-1R in Proliferating Islets of Men1 Mice is Detectable by [(68)Ga]Ga-DO3A-VS-Cys(40)-Exendin-4 /PET

Multiple endocrine neoplasia type 1 (MEN1) is an endocrine tumor syndrome caused by heterozygous mutations in the MEN1 tumor suppressor gene. The MEN1 pancreas of the adolescent gene carrier frequently contain diffusely spread pre-neoplasias and microadenomas, progressing to macroscopic and potentia...

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Detalles Bibliográficos
Autores principales: Monazzam, Azita, Lau, Joey, Velikyan, Irina, Li, Su-Chen, Razmara, Masoud, Rosenström, Ulrika, Eriksson, Olof, Skogseid, Britt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768696/
https://www.ncbi.nlm.nih.gov/pubmed/29335487
http://dx.doi.org/10.1038/s41598-017-18855-0