Causal associations between risk factors and common diseases inferred from GWAS summary data

Health risk factors such as body mass index (BMI) and serum cholesterol are associated with many common diseases. It often remains unclear whether the risk factors are cause or consequence of disease, or whether the associations are the result of confounding. We develop and apply a method (called GS...

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Detalles Bibliográficos
Autores principales: Zhu, Zhihong, Zheng, Zhili, Zhang, Futao, Wu, Yang, Trzaskowski, Maciej, Maier, Robert, Robinson, Matthew R., McGrath, John J., Visscher, Peter M., Wray, Naomi R., Yang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768719/
https://www.ncbi.nlm.nih.gov/pubmed/29335400
http://dx.doi.org/10.1038/s41467-017-02317-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768719/
https://www.ncbi.nlm.nih.gov/pubmed/29335400
http://dx.doi.org/10.1038/s41467-017-02317-2

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