A partially-open inward-facing intermediate conformation of LeuT is associated with Na(+) release and substrate transport

Neurotransmitter:sodium symporters (NSS), targets of antidepressants and psychostimulants, clear neurotransmitters from the synaptic cleft through sodium (Na(+))-coupled transport. Substrate and Na(+) are thought to be transported from the extracellular to intracellular space through an alternating...

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Detalles Bibliográficos
Autores principales: Terry, Daniel S., Kolster, Rachel A., Quick, Matthias, LeVine, Michael V., Khelashvili, George, Zhou, Zhou, Weinstein, Harel, Javitch, Jonathan A., Blanchard, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768729/
https://www.ncbi.nlm.nih.gov/pubmed/29335402
http://dx.doi.org/10.1038/s41467-017-02202-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768729/
https://www.ncbi.nlm.nih.gov/pubmed/29335402
http://dx.doi.org/10.1038/s41467-017-02202-y

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