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Structure of a MacAB-like efflux pump from Streptococcus pneumoniae

The spr0693-spr0694-spr0695 operon of Streptococcus pneumoniae encodes a putative ATP-binding cassette (ABC)-type efflux pump involved in the resistance of antibiotics and antimicrobial peptides. Here we report the crystal structures of Spr0694–0695 at 3.3 Å and Spr0693 at 3.0 Å resolution, revealin...

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Detalles Bibliográficos
Autores principales: Yang, Hong-Bo, Hou, Wen-Tao, Cheng, Meng-Ting, Jiang, Yong-Liang, Chen, Yuxing, Zhou, Cong-Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768738/
https://www.ncbi.nlm.nih.gov/pubmed/29335499
http://dx.doi.org/10.1038/s41467-017-02741-4