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Dual functional dinuclear platinum complex with selective reactivity towards c-myc G-quadruplex

G-quadruplexes (GQ) folded by the oncogenic G-rich sequences are the promising targets for developing anticancer therapeutic molecules. However, the current drug development mainly focused on non-covalent dynamic binders to stabilize GQ structures, while the covalent targeting from inorganic complex...

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Detalles Bibliográficos
Autores principales:	He, Lei, Meng, Zhenyu, Xu, Dechen, Shao, Fangwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768759/ https://www.ncbi.nlm.nih.gov/pubmed/29335501 http://dx.doi.org/10.1038/s41598-017-19095-y

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