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Radical asymmetric intramolecular α-cyclopropanation of aldehydes towards bicyclo[3.1.0]hexanes containing vicinal all-carbon quaternary stereocenters

The development of a general catalytic method for the direct and stereoselective construction of cyclopropanes bearing highly congested vicinal all-carbon quaternary stereocenters remains a formidable challenge in chemical synthesis. Here, we report an intramolecular radical cyclopropanation of unac...

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Detalles Bibliográficos
Autores principales:	Ye, Liu, Gu, Qiang-Shuai, Tian, Yu, Meng, Xiang, Chen, Guo-Cong, Liu, Xin-Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768789/ https://www.ncbi.nlm.nih.gov/pubmed/29335407 http://dx.doi.org/10.1038/s41467-017-02231-7

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