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Transcriptomic signatures of cellular and humoral immune responses in older adults after seasonal influenza vaccination identified by data-driven clustering

PBMC transcriptomes after influenza vaccination contain valuable information about factors affecting vaccine responses. However, distilling meaningful knowledge out of these complex datasets is often difficult and requires advanced data mining algorithms. We investigated the use of the data-driven W...

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Detalles Bibliográficos
Autores principales: Voigt, Emily A., Grill, Diane E., Zimmermann, Michael T., Simon, Whitney L., Ovsyannikova, Inna G., Kennedy, Richard B., Poland, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768803/
https://www.ncbi.nlm.nih.gov/pubmed/29335477
http://dx.doi.org/10.1038/s41598-017-17735-x