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Generation of Adrenal Chromaffin-like Cells from Human Pluripotent Stem Cells

Adrenomedullary chromaffin cells are catecholamine (CA)-producing cells originating from trunk neural crest (NC) via sympathoadrenal progenitors (SAPs). We generated NC and SAPs from human embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) in vitro via BMP2/FGF2 exposure, ascerta...

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Detalles Bibliográficos
Autores principales: Abu-Bonsrah, Kwaku Dad, Zhang, Dongcheng, Bjorksten, Andrew R., Dottori, Mirella, Newgreen, Donald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768882/
https://www.ncbi.nlm.nih.gov/pubmed/29233551
http://dx.doi.org/10.1016/j.stemcr.2017.11.003