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Breast Cancers Activate Stromal Fibroblast-Induced Suppression of Progenitors in Adjacent Normal Tissue

Human breast cancer cells are known to activate adjacent “normal-like” cells to enhance their own growth, but the cellular and molecular mechanisms involved are poorly understood. We now show by both phenotypic and functional measurements that normal human mammary progenitor cells are significantly...

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Detalles Bibliográficos
Autores principales: Chatterjee, Sumanta, Basak, Pratima, Buchel, Edward, Safneck, Janice, Murphy, Leigh C., Mowat, Michael, Kung, Sam K., Eirew, Peter, Eaves, Connie J., Raouf, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768884/
https://www.ncbi.nlm.nih.gov/pubmed/29233553
http://dx.doi.org/10.1016/j.stemcr.2017.11.002