Cargando…
Breast Cancers Activate Stromal Fibroblast-Induced Suppression of Progenitors in Adjacent Normal Tissue
Human breast cancer cells are known to activate adjacent “normal-like” cells to enhance their own growth, but the cellular and molecular mechanisms involved are poorly understood. We now show by both phenotypic and functional measurements that normal human mammary progenitor cells are significantly...
Autores principales: | Chatterjee, Sumanta, Basak, Pratima, Buchel, Edward, Safneck, Janice, Murphy, Leigh C., Mowat, Michael, Kung, Sam K., Eirew, Peter, Eaves, Connie J., Raouf, Afshin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768884/ https://www.ncbi.nlm.nih.gov/pubmed/29233553 http://dx.doi.org/10.1016/j.stemcr.2017.11.002 |
Ejemplares similares
-
Adipose-Derived Stromal Vascular Fraction Differentially Expands Breast Progenitors in Tissue Adjacent to Tumors Compared to Healthy Breast Tissue
por: Chatterjee, Sumanta, et al.
Publicado: (2015) -
A robust cell culture system for large scale feeder cell-free expansion of human breast epithelial progenitors
por: Chatterjee, Sumanta, et al.
Publicado: (2018) -
Paracrine Crosstalk between Fibroblasts and ER(+) Breast Cancer Cells Creates an IL1β-Enriched Niche that Promotes Tumor Growth
por: Chatterjee, Sumanta, et al.
Publicado: (2019) -
Estrogen regulates luminal progenitor cell differentiation through H19 gene expression
por: Basak, Pratima, et al.
Publicado: (2015) -
The Deleted in Liver Cancer 1 (Dlc1) tumor suppressor is haploinsufficient for mammary gland development and epithelial cell polarity
por: Basak, Pratima, et al.
Publicado: (2015)