Cisplatin and Pemetrexed Activate AXL and AXL Inhibitor BGB324 Enhances Mesothelioma Cell Death from Chemotherapy

Reactive oxygen species (ROS) can promote or inhibit tumorigenesis. In mesothelioma, asbestos exposure to serous membranes induces ROS through iron content and chronic inflammation, and ROS promote cell survival signaling in mesothelioma. Moreover, a current chemotherapy regimen for mesothelioma con...

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Detalles Bibliográficos
Autores principales: Oien, Derek B., Garay, Tamás, Eckstein, Sarah, Chien, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768913/
https://www.ncbi.nlm.nih.gov/pubmed/29375377
http://dx.doi.org/10.3389/fphar.2017.00970

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768913/
https://www.ncbi.nlm.nih.gov/pubmed/29375377
http://dx.doi.org/10.3389/fphar.2017.00970

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