HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway

Here, we show that HEMATOLOGICAL AND NEUROLOGICAL EXPRESSED 1-LIKE (HN1L) is a targetable breast cancer stem cell (BCSC) gene that is altered in 25% of whole breast cancer and significantly correlated with shorter overall or relapse-free survival in triple-negative breast cancer (TNBC) patients. HN1...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Choi, Dong Soon, Sheng, Jianting, Ensor, Joe E., Liang, Diana Hwang, Rodriguez-Aguayo, Cristian, Polley, Amanda, Benz, Steve, Elemento, Olivier, Verma, Akanksha, Cong, Yang, Wong, Helen, Qian, Wei, Li, Zheng, Granados-Principal, Sergio, Lopez-Berestein, Gabriel, Landis, Melissa D., Rosato, Roberto R., Dave, Bhuvanesh, Wong, Stephen, Marchetti, Dario, Sood, Anil K., Chang, Jenny C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768915/
https://www.ncbi.nlm.nih.gov/pubmed/29249663
http://dx.doi.org/10.1016/j.stemcr.2017.11.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768915/
https://www.ncbi.nlm.nih.gov/pubmed/29249663
http://dx.doi.org/10.1016/j.stemcr.2017.11.010

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