Modeling the Pathogenesis of Charcot-Marie-Tooth Disease Type 1A Using Patient-Specific iPSCs

Charcot-Marie-Tooth disease type 1A (CMT1A), one of the most frequent inherited peripheral neuropathies, is associated with PMP22 gene duplication. Previous studies of CMT1A mainly relied on rodent models, and it is not yet clear how PMP22 overexpression leads to the phenotype in patients. Here, we...

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Detalles Bibliográficos
Autores principales: Shi, Lei, Huang, Lihua, He, Ruojie, Huang, Weijun, Wang, Huiyan, Lai, Xingqiang, Zou, Zhengwei, Sun, Jiaqi, Ke, Qiong, Zheng, Minying, Lu, Xilin, Pei, Zhong, Su, Huanxing, Xiang, Andy Peng, Li, Weiqiang, Yao, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768917/
https://www.ncbi.nlm.nih.gov/pubmed/29276154
http://dx.doi.org/10.1016/j.stemcr.2017.11.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768917/
https://www.ncbi.nlm.nih.gov/pubmed/29276154
http://dx.doi.org/10.1016/j.stemcr.2017.11.013

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