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Hepatitis C virus core protein-induced miR-93-5p up-regulation inhibits interferon signaling pathway by targeting IFNAR1

AIM: To investigate the mechanism by which hepatitis C virus (HCV) core protein-induced miR-93-5p up-regulation regulates the interferon (IFN) signaling pathway. METHODS: HCV-1b core protein was exogenously expressed in Huh7 cells using pcDNA3.1 (+) vector. The expression of miR-93-5p and interferon...

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Detalles Bibliográficos
Autores principales: He, Chang-Long, Liu, Ming, Tan, Zhao-Xia, Hu, Ya-Jun, Zhang, Qiao-Yue, Kuang, Xue-Mei, Kong, Wei-Long, Mao, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768941/
https://www.ncbi.nlm.nih.gov/pubmed/29375208
http://dx.doi.org/10.3748/wjg.v24.i2.226