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BMAL1 Deficiency Contributes to Mandibular Dysplasia by Upregulating MMP3

Skeletal mandibular hypoplasia (SMH), one of the common types of craniofacial deformities, seriously affects appearance, chewing, pronunciation, and breathing. Moreover, SMH is prone to inducing obstructive sleep apnea syndrome. We found that brain and muscle ARNT-like 1 (BMAL1), the core component...

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Detalles Bibliográficos
Autores principales: Zhao, Jiajia, Zhou, Xin, Tang, Qingming, Yu, Ran, Yu, Shaoling, Long, Yanlin, Cao, Cen, Han, Jun, Shi, Anbing, Mao, Jeremy J., Chen, Xiong, Chen, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768965/
https://www.ncbi.nlm.nih.gov/pubmed/29276151
http://dx.doi.org/10.1016/j.stemcr.2017.11.017