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Revolutionizing male fertility factor research in mice by using the genome editing tool CRISPR/Cas9

BACKGROUND: Reproductive research is quintessential in understanding not only the cause of infertility, but also for creating family planning tools. The knockout (KO) system approach is conducive to discovering genes that are essential for fertility in mice. However, in vivo research has been limite...

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Detalles Bibliográficos
Autores principales: Abbasi, Ferheen, Miyata, Haruhiko, Ikawa, Masahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768971/
https://www.ncbi.nlm.nih.gov/pubmed/29371815
http://dx.doi.org/10.1002/rmb2.12067