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Inhibition of Inwardly Rectifying Potassium (Kir) 4.1 Channels Facilitates Brain-Derived Neurotrophic Factor (BDNF) Expression in Astrocytes

Inwardly rectifying potassium (Kir) 4.1 channels in astrocytes regulate neuronal excitability by mediating spatial potassium buffering. Although dysfunction of astrocytic Kir4.1 channels is implicated in the development of epileptic seizures, the functional mechanisms of Kir4.1 channels in modulatin...

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Detalles Bibliográficos
Autores principales: Kinboshi, Masato, Mukai, Takahiro, Nagao, Yuki, Matsuba, Yusuke, Tsuji, Yoshimi, Tanaka, Shiho, Tokudome, Kentaro, Shimizu, Saki, Ito, Hidefumi, Ikeda, Akio, Inanobe, Atsushi, Kurachi, Yoshihisa, Inoue, Seiji, Ohno, Yukihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768989/
https://www.ncbi.nlm.nih.gov/pubmed/29358904
http://dx.doi.org/10.3389/fnmol.2017.00408