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Evaluation of Metabolic and Synaptic Dysfunction Hypotheses of Alzheimer’s Disease (AD): A Meta-Analysis of CSF Markers

BACKGROUND: Alzheimer’s disease (AD) is currently incurable and a majority of investigational drugs have failed clinical trials. One explanation for this failure may be the invalidity of hypotheses focus-ing on amyloid to explain AD pathogenesis. Recently, hypotheses which are centered on synaptic a...

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Detalles Bibliográficos
Autores principales: Manyevitch, Roni, Protas, Matthew, Scarpiello, Sean, Deliso, Marisa, Bass, Brittany, Nanajian, Anthony, Chang, Matthew, Thompson, Stefani M., Khoury, Neil, Gonnella, Rachel, Trotz, Margit, Moore, D. Blaine, Harms, Emily, Perry, George, Clunes, Lucy, Ortiz, Angélica, Friedrich, Jan O., Murray, Ian V.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769087/
https://www.ncbi.nlm.nih.gov/pubmed/28933272
http://dx.doi.org/10.2174/1567205014666170921122458