Human UDP-Glucuronosyltransferase 2B4 and 2B7 Are Responsible for Naftopidil Glucuronidation in Vitro

Naftopidil (NAF) is widely used for the treatment of benign prostatic hyperplasia and prevention of prostate cancer in elderly men. These patients receive a combination of drugs, which involves high risk for drug–drug interaction. NAF exhibits superior efficacy but must be administered at a much hig...

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Detalles Bibliográficos
Autores principales: Liu, Xia-Wen, Rong, Yi, Zhang, Xing-Fei, Huang, Jun-Jun, Cai, Yi, Huang, Bi-Yun, Zhu, Liu, Wu, Bo, Hou, Ning, Luo, Cheng-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769128/
https://www.ncbi.nlm.nih.gov/pubmed/29375383
http://dx.doi.org/10.3389/fphar.2017.00984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769128/
https://www.ncbi.nlm.nih.gov/pubmed/29375383
http://dx.doi.org/10.3389/fphar.2017.00984

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