Cargando…
Human UDP-Glucuronosyltransferase 2B4 and 2B7 Are Responsible for Naftopidil Glucuronidation in Vitro
Naftopidil (NAF) is widely used for the treatment of benign prostatic hyperplasia and prevention of prostate cancer in elderly men. These patients receive a combination of drugs, which involves high risk for drug–drug interaction. NAF exhibits superior efficacy but must be administered at a much hig...
Autores principales: | Liu, Xia-Wen, Rong, Yi, Zhang, Xing-Fei, Huang, Jun-Jun, Cai, Yi, Huang, Bi-Yun, Zhu, Liu, Wu, Bo, Hou, Ning, Luo, Cheng-Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769128/ https://www.ncbi.nlm.nih.gov/pubmed/29375383 http://dx.doi.org/10.3389/fphar.2017.00984 |
Ejemplares similares
-
Dysregulated hepatic UDP-glucuronosyltransferases and flavonoids glucuronidation in experimental colitis
por: Zeng, Wanying, et al.
Publicado: (2022) -
Contributions of UDP-Glucuronosyltransferases to Human Hepatic and Intestinal Metabolism of Ticagrelor and Inhibition of UGTs and Cytochrome P450 Enzymes by Ticagrelor and its Glucuronidated Metabolite
por: Liu, Shuaibing, et al.
Publicado: (2021) -
Glucuronidation of drugs in humanized UDP-glucuronosyltransferase 1 mice: Similarity with glucuronidation in human liver microsomes
por: Kutsuno, Yuki, et al.
Publicado: (2013) -
Identification of Human UDP-Glucuronosyltransferase Involved in Gypensapogenin C Glucuronidation and Species Differences
por: Chen, Juan, et al.
Publicado: (2023) -
In Vitro Glucuronidation of Wushanicaritin by Liver Microsomes, Intestine Microsomes and Expressed Human UDP-Glucuronosyltransferase Enzymes
por: Hong, Xiaodan, et al.
Publicado: (2017)