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Mitochondrial Complex I Inhibition Accelerates Amyloid Toxicity

Alzheimer's disease (AD) is neurodegenerative disease, characterized by the progressive decline of memory, cognitive functions, and changes in personality. The major pathological features in postmortem brains are neurofibrillary tangles and amyloid beta (Aβ) deposits. The majority of AD cases a...

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Detalles Bibliográficos
Autores principales: Joh, Yechan, Choi, Won-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Developmental Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769135/
https://www.ncbi.nlm.nih.gov/pubmed/29354787
http://dx.doi.org/10.12717/DR.2017.21.4.417