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Ultrasound-targeted microbubble destruction-mediated Foxp3 knockdown may suppress the tumor growth of HCC mice by relieving immunosuppressive Tregs function

The aim of the present study was to investigate the effect of Forkhead family transcription factor P3 (Foxp3) knockdown on the function of cluster of differentiation (CD)4(+)CD25(+) regulatory T cell (Tregs) and the tumor growth of a hepatocellular carcinoma (HCC) mouse model. CD4(+)CD25(+) Tregs an...

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Detalles Bibliográficos
Autores principales: Shi, Chunying, Zhang, Yu, Yang, Haichao, Dong, Tianxiu, Chen, Yaodong, Xu, Yutong, Yang, Xiuhua, Liu, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769241/
https://www.ncbi.nlm.nih.gov/pubmed/29387180
http://dx.doi.org/10.3892/etm.2017.5421