Rare variant association analysis in case-parents studies by allowing for missing parental genotypes

BACKGROUND: The development of next-generation sequencing technologies has facilitated the identification of rare variants. Family-based design is commonly used to effectively control for population admixture and substructure, which is more prominent for rare variants. Case-parents studies, as typic...

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Detalles Bibliográficos
Autores principales: Li, Yumei, Xiang, Yang, Xu, Chao, Shen, Hui, Deng, Hongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769338/
https://www.ncbi.nlm.nih.gov/pubmed/29334894
http://dx.doi.org/10.1186/s12863-018-0597-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769338/
https://www.ncbi.nlm.nih.gov/pubmed/29334894
http://dx.doi.org/10.1186/s12863-018-0597-8

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