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Rare variant association analysis in case-parents studies by allowing for missing parental genotypes
BACKGROUND: The development of next-generation sequencing technologies has facilitated the identification of rare variants. Family-based design is commonly used to effectively control for population admixture and substructure, which is more prominent for rare variants. Case-parents studies, as typic...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769338/ https://www.ncbi.nlm.nih.gov/pubmed/29334894 http://dx.doi.org/10.1186/s12863-018-0597-8 |