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Is cancer progression caused by gradual or simultaneous acquisitions of new chromosomes?
BACKGROUND: Foulds defined, “Tumor progression (as a) permanent, irreversible qualitative change in one or more of its characters” (Cancer Res. 1954). Accordingly progressions, such as metastases and acquired drug-resistance, were since found to be subspecies of cancers with conserved and numerous n...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769399/ https://www.ncbi.nlm.nih.gov/pubmed/29371887 http://dx.doi.org/10.1186/s13039-017-0350-4 |