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Epidermal Wnt signalling regulates transcriptome heterogeneity and proliferative fate in neighbouring cells
BACKGROUND: Canonical Wnt/beta-catenin signalling regulates self-renewal and lineage selection within the mammalian epidermis. Although the transcriptional response of keratinocytes that receive a Wnt signal is well characterized, little is known about the mechanism by which keratinocytes in proximi...
Autores principales: | Ghahramani, Arsham, Donati, Giacomo, Luscombe, Nicholas M., Watt, Fiona M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769491/ https://www.ncbi.nlm.nih.gov/pubmed/29334988 http://dx.doi.org/10.1186/s13059-017-1384-y |
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