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ICG-001 Exerts Potent Anticancer Activity Against Uveal Melanoma Cells

PURPOSE: Uveal melanoma (UM) is uniformly refractory to all available systemic chemotherapies, thus creating an urgent need for novel therapeutics. In this study, we investigated the sensitivity of UM cells to ICG-001, a small molecule reported to suppress the Wnt/β-catenin–mediated transcriptional...

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Detalles Bibliográficos
Autores principales: Kaochar, Salma, Dong, Jianrong, Torres, Marie, Rajapakshe, Kimal, Nikolos, Fotis, Davis, Christel M., Ehli, Erik A., Coarfa, Cristian, Mitsiades, Nicholas, Poulaki, Vasiliki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769500/
https://www.ncbi.nlm.nih.gov/pubmed/29332125
http://dx.doi.org/10.1167/iovs.17-22454