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Mendelian randomization analysis to assess a causal effect of haptoglobin on macroangiopathy in Chinese type 2 diabetes patients

BACKGROUND: Haptoglobin (Hp) functions as an antioxidant by binding with haemoglobin. We investigated whether serum Hp has a causal effect on macroangiopathy via Mendelian randomization (MR) analysis with common variants of the Hp gene in Chinese patients with type 2 diabetes. METHODS: A total of 56...

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Detalles Bibliográficos
Autores principales: Wang, Shiyun, Wang, Jie, Zhang, Rong, Wang, Tao, Yan, Dandan, He, Zhen, Jiang, Feng, Hu, Cheng, Jia, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769522/
https://www.ncbi.nlm.nih.gov/pubmed/29338727
http://dx.doi.org/10.1186/s12933-018-0662-7