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A novel IL-1RA-PEP fusion protein alleviates blood-brain barrier disruption after ischemia-reperfusion in male rats

BACKGROUND: Current options to treat clinical relapse in inflammatory central nervous system (CNS) conditions such as cerebral ischemia-reperfusion injury are limited, and agents that are more effective are required. Disruption of the blood-brain barrier is an early feature of lesion formation that...

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Detalles Bibliográficos
Autores principales: Zhang, Dong-Dong, Jin, Chen, Zhang, Ya-Tao, Gan, Xiang-Dong, Zou, Min-Ji, Wang, Yuan-Yuan, Fu, Wen-Liang, Xu, Tao, Xing, Wei-Wei, Xia, Wen-Ron, Xu, Dong-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769540/
https://www.ncbi.nlm.nih.gov/pubmed/29334965
http://dx.doi.org/10.1186/s12974-018-1058-z