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Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF)

Dysregulation of VEGF-A bioavailability has been implicated in the development of lung injury/fibrosis, exemplified by Idiopathic Pulmonary Fibrosis (IPF). VEGF-A is a target of the hypoxic response via its translational regulation by HIF-1α. The role of hypoxia and hyperoxia in the development and...

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Detalles Bibliográficos
Autores principales: Barratt, Shaney L., Blythe, Thomas, Ourradi, Khadija, Jarrett, Caroline, Welsh, Gavin I., Bates, David O., Millar, Ann B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769544/
https://www.ncbi.nlm.nih.gov/pubmed/29334947
http://dx.doi.org/10.1186/s12931-017-0711-x