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Effects of hypoxia and hyperoxia on the differential expression of VEGF-A isoforms and receptors in Idiopathic Pulmonary Fibrosis (IPF)
Dysregulation of VEGF-A bioavailability has been implicated in the development of lung injury/fibrosis, exemplified by Idiopathic Pulmonary Fibrosis (IPF). VEGF-A is a target of the hypoxic response via its translational regulation by HIF-1α. The role of hypoxia and hyperoxia in the development and...
Autores principales: | Barratt, Shaney L., Blythe, Thomas, Ourradi, Khadija, Jarrett, Caroline, Welsh, Gavin I., Bates, David O., Millar, Ann B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769544/ https://www.ncbi.nlm.nih.gov/pubmed/29334947 http://dx.doi.org/10.1186/s12931-017-0711-x |
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