Dose reduction of bone morphogenetic protein-2 for bone regeneration using a delivery system based on lyophilization with trehalose

INTRODUCTION: To induce sufficient new bone formation, high doses of bone morphogenetic protein-2 (BMP-2) are applied in regenerative medicine that often induce serious side effects. Therefore, improved treatment strategies are required. Here, we investigate whether the delivery of BMP-2 lyophilized...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaochen, Yu, Quan, Wang, Yan-an, Zhao, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769568/
https://www.ncbi.nlm.nih.gov/pubmed/29391797
http://dx.doi.org/10.2147/IJN.S150875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769568/
https://www.ncbi.nlm.nih.gov/pubmed/29391797
http://dx.doi.org/10.2147/IJN.S150875

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