Cargando…

Dose reduction of bone morphogenetic protein-2 for bone regeneration using a delivery system based on lyophilization with trehalose

INTRODUCTION: To induce sufficient new bone formation, high doses of bone morphogenetic protein-2 (BMP-2) are applied in regenerative medicine that often induce serious side effects. Therefore, improved treatment strategies are required. Here, we investigate whether the delivery of BMP-2 lyophilized...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiaochen, Yu, Quan, Wang, Yan-an, Zhao, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769568/ https://www.ncbi.nlm.nih.gov/pubmed/29391797 http://dx.doi.org/10.2147/IJN.S150875

Ejemplares similares

Formulation, Delivery and Stability of Bone Morphogenetic Proteins for Effective Bone Regeneration
por: El Bialy, Inas, et al.
Publicado: (2017)

Bone Morphogenetic Proteins: Periodontal Regeneration
por: Rao, Subramaniam M, et al.
Publicado: (2013)

Delivery of bone morphogenetic protein-2 and substance P using graphene oxide for bone regeneration
por: La, Wan-Geun, et al.
Publicado: (2014)

Heparin-mediated delivery of bone morphogenetic protein-2 improves spatial localization of bone regeneration
por: Hettiaratchi, Marian H., et al.
Publicado: (2020)

Bone morphogenetic proteins: Signaling periodontal bone regeneration and repair
por: Anusuya, G. Sai, et al.
Publicado: (2016)

Bone Morphogenetic Proteins for Nucleus Pulposus Regeneration
por: Krouwels, Anita, et al.
Publicado: (2020)

Bone Regeneration Using Bone Morphogenetic Proteins and Various Biomaterial Carriers
por: Sheikh, Zeeshan, et al.
Publicado: (2015)

Carrier systems for bone morphogenetic proteins: An overview of biomaterials used for dentoalveolar and maxillofacial bone regeneration
por: Arias-Betancur, Alain, et al.
Publicado: (2022)

Cell recognitive bioadhesive‐based osteogenic barrier coating with localized delivery of bone morphogenetic protein‐2 for accelerated guided bone regeneration
por: Jo, Yun Kee, et al.
Publicado: (2023)

Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery
por: Tolstyka, Zachary P., et al.
Publicado: (2015)

Sustained delivery of the bone morphogenetic proteins BMP-2 and BMP-7 for cartilage repair and regeneration in osteoarthritis
por: Whitty, Ciara, et al.
Publicado: (2022)

Comparison of Bone Regeneration in Different Forms of Bovine Bone Scaffolds with Recombinant Human Bone Morphogenetic Protein-2
por: Seok, Hyun, et al.
Publicado: (2021)

Correction to Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery
por: Tolstyka, Zachary P., et al.
Publicado: (2017)

Stepwise verification of bone regeneration using recombinant human bone morphogenetic protein-2 in rat fibula model
por: Nam, Jung-Woo, et al.
Publicado: (2017)

Stimulation of Bone Healing by Sustained Bone Morphogenetic Protein 2 (BMP-2) Delivery
por: Faßbender, Mirja, et al.
Publicado: (2014)

The Classic: Bone Morphogenetic Protein
por: Urist, Marshall R., et al.
Publicado: (2009)

Bone morphogenetic protein-4 and bone morphogenetic protein receptors expressions in the adult rat eye
por: Maruyama-Koide, Yuka, et al.
Publicado: (2017)

In vitro evaluation of a bone morphogenetic protein-2 nanometer hydroxyapatite collagen scaffold for bone regeneration
por: Cai, Yue, et al.
Publicado: (2018)

Enhanced osteogenic activity and anti-inflammatory properties of Lenti-BMP-2-loaded TiO(2) nanotube layers fabricated by lyophilization following trehalose addition
por: Zhang, Xiaochen, et al.
Publicado: (2016)

Trehalose Maintains Bioactivity and Promotes Sustained Release of BMP-2 from Lyophilized CDHA Scaffolds for Enhanced Osteogenesis In Vitro and In Vivo
por: Zhao, Jun, et al.
Publicado: (2013)

Preparation and characterization of 3D hydroxyapatite/collagen scaffolds and its application in bone regeneration with bone morphogenetic protein-2
por: Xie, Hongyu, et al.
Publicado: (2023)

Bone Morphogenetic Protein-2 in Development and Bone Homeostasis
por: Halloran, Daniel, et al.
Publicado: (2020)

Engineered bridge protein with dual affinity for bone morphogenetic protein-2 and collagen enhances bone regeneration for spinal fusion
por: Briquez, Priscilla S., et al.
Publicado: (2021)

Comparison between heparin-conjugated fibrin and collagen sponge as bone morphogenetic protein-2 carriers for bone regeneration
por: Yang, Hee Seok, et al.
Publicado: (2012)

Polyethylenimine-alginate nanocomposites based bone morphogenetic protein 2 gene-activated matrix for alveolar bone regeneration
por: Jin, Han, et al.
Publicado: (2019)

Nuclear variants of bone morphogenetic proteins
por: Felin, Jenny E, et al.
Publicado: (2010)

Bone morphogenetic protein guts it out
por: Leslie, Mitch
Publicado: (2013)

Bone morphogenetic proteins: The anomalous molecules
por: Jain, Aena Pundir, et al.
Publicado: (2013)

Bone Morphogenetic Proteins and Diabetic Retinopathy
por: Elmasry, Khaled, et al.
Publicado: (2021)

Insights into bone morphogenetic proteins in cardiovascular diseases
por: Ye, Di, et al.
Publicado: (2023)

Regeneration of Bone- and Tendon/Ligament-Like Tissues Induced by Gene Transfer of Bone Morphogenetic Protein-12 in a Rat Bone Defect
por: Kuroda, Shinji, et al.
Publicado: (2010)

Sustained delivery of recombinant human bone morphogenetic protein-2 from perlecan domain I - functionalized electrospun poly (ε-caprolactone) scaffolds for bone regeneration
por: Chiu, Yu-Chieh, et al.
Publicado: (2016)

Bacterial cellulose membrane functionalized with hydroxiapatite and anti-bone morphogenetic protein 2: A promising material for bone regeneration
por: Coelho, Fernanda, et al.
Publicado: (2019)

Bone morphogenetic protein 4 is involved in cadmium-associated bone damage
por: Wan, Yu, et al.
Publicado: (2022)

Lyophilized Platelet-Rich Fibrin (PRF) Promotes Craniofacial Bone Regeneration through Runx2
por: Li, Qi, et al.
Publicado: (2014)

Controlled Release Strategies for the Combination of Fresh and Lyophilized Platelet-Rich Fibrin on Bone Tissue Regeneration
por: Liu, Zhongshuang, et al.
Publicado: (2019)

Comparative analysis of carrier systems for delivering bone morphogenetic proteins
por: Jung, Im-Hee, et al.
Publicado: (2015)

The biology of bone morphogenetic protein signaling pathway in cerebrovascular system
por: Tang, Haishuang, et al.
Publicado: (2021)

PHYSICOCHEMICAL CHARACTERIZATION OF LYOPHILIZED BOVINE BONE GRAFTS
por: Galia, Carlos Roberto, et al.
Publicado: (2015)

Lyophilized allogeneic bone tissue as an antibiotic carrier
por: Coraça-Huber, Débora C., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_ml8350lv994ptjr0eut18kllfc