The silencing of LncRNA-H19 decreases chemoresistance of human glioma cells to temozolomide by suppressing epithelial-mesenchymal transition via the Wnt/β-Catenin pathway

INTRODUCTION: Temozolomide (TMZ) is commonly used for glioma chemotherapy. However, TMZ resistance limits the therapeutic effect of TMZ in glioma treatment. LncRNA-H19 acts as an oncogenic LncRNA in some types of cancers and has been reported to be up-regulated in glioma. MATERIALS AND METHODS: In o...

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Detalles Bibliográficos
Autores principales: Jia, Linwei, Tian, Yaohui, Chen, Yonghan, Zhang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769571/
https://www.ncbi.nlm.nih.gov/pubmed/29391808
http://dx.doi.org/10.2147/OTT.S154339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769571/
https://www.ncbi.nlm.nih.gov/pubmed/29391808
http://dx.doi.org/10.2147/OTT.S154339

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