Cargando…

Giantin-knockout models reveal a feedback loop between Golgi function and glycosyltransferase expression

The Golgi is the cellular hub for complex glycosylation, controlling accurate processing of complex proteoglycans, receptors, ligands and glycolipids. Its structure and organisation are dependent on golgins, which tether cisternal membranes and incoming transport vesicles. Here, we show that knockou...

Descripción completa

Detalles Bibliográficos
Autores principales: Stevenson, Nicola L., Bergen, Dylan J. M., Skinner, Roderick E. H., Kague, Erika, Martin-Silverstone, Elizabeth, Robson Brown, Kate A., Hammond, Chrissy L., Stephens, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769581/
https://www.ncbi.nlm.nih.gov/pubmed/29093022
http://dx.doi.org/10.1242/jcs.212308