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Renal carcinoma/kidney progenitor cell chimera organoid as a novel tumorigenesis gene discovery model

Three-dimensional (3D) organoids provide a new way to model various diseases, including cancer. We made use of recently developed kidney-organ-primordia tissue-engineering technologies to create novel renal organoids for cancer gene discovery. We then tested whether our novel assays can be used to e...

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Detalles Bibliográficos
Autores principales: Xu, Qi, Junttila, Sanna, Scherer, Andreas, Giri, Khem Raj, Kivelä, Oona, Skovorodkin, Ilya, Röning, Juha, Quaggin, Susan E., Marti, Hans-Peter, Shan, Jingdong, Samoylenko, Anatoly, Vainio, Seppo J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5769601/
https://www.ncbi.nlm.nih.gov/pubmed/29084770
http://dx.doi.org/10.1242/dmm.028332